论文部分内容阅读
本工作通过改变人工呼吸的通气量使肺泡气的CO_2浓度发生变化,观察其对猫脑干中缝大核区神经细胞自发放电的影响。发现每个神经细胞都有自己稳定放电的肺泡气CO_2浓度范围。有些神经细胞,这个浓度范围很小,对肺泡气CO_2浓度的改变非常敏感,而有少数神经细胞对肺泡气CO_2浓度的改变则很不敏感。当肺泡气CO_2浓度越出稳定放电的肺泡气CO_2浓度范围后,神经细胞的放电就会减少,或者增加。根据反应的不同,可将细胞分为三类:第一类细胞,当肺泡气CO_2浓度小于稳定放电的CO_2浓度范围时,放电减少;而当大于稳定放电的CO_2浓度范围时,放电增多。第二类细胞,当肺泡气CO_2浓度小于稳定放电的CO_2浓度范围时,放电增多;而当大于稳定放电的CO_2浓度范围时,放电减少。第三类细胞,当肺泡气CO_2浓度小于或大于稳定放电的CO_2浓度范围时,放电均减少。
In this work, the CO 2 concentration in alveolar gas was changed by changing the ventilation rate of artificial respiration, and the effect on spontaneous discharge of nerve cells in the nucleus raphe magnus of cat brainstem was observed. Found that each nerve cell has its own stable discharge of alveolar gas CO 2 concentration range. In some neurons, this concentration range is very small, very sensitive to the change of CO 2 concentration in alveolar gas, while a small number of nerve cells are very insensitive to the change of CO 2 concentration in alveolar gas. When the concentration of CO 2 in the alveolar gas exceeds the range of CO 2 concentration in the stable discharge of alveolar gas, the discharge of the nerve cells decreases or increases. According to the different reactions, the cells can be divided into three groups: the first type of cells, when the CO 2 concentration of alveolar gas is less than the stable discharge CO 2 concentration range, the discharge decreases; and when greater than the stable discharge CO 2 concentration range, the discharge increased. The second type of cells, when the CO 2 concentration in the alveolar gas is less than the stable discharge CO 2 concentration range, the discharge increases; and when the CO 2 concentration range is greater than the steady discharge, the discharge decreases. The third type of cells, when the alveolar gas CO 2 concentration is less than or greater than the stable discharge CO 2 concentration range, the discharge is reduced.