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目的 探讨AOPP 时特效解毒剂合理应用的方法。方法 采用对照研究的方法,将1998 年4 月—1998 年12 月间收治的AOPP住院病人分为治疗组及对照组各20 人,在综合内科治疗的基础上,分度给特效解毒剂。治疗组早期、足量、反复应用复能剂辅小剂量阿托品,复能剂用5 —7 天;对照组按传统的方法应用复能剂及阿托品,复能剂用3 天。结果 比较两组间阿托品、复能剂用量,并发症发生率及住院天数均有显著性差异( P< 001) ;治愈率无差异( P> 005) ,但治疗组临床状况优于对照组。结论 应用本方案救治AOPP,可减少阿托品复合中毒,有效的防治中间综合症,从而改变其自然病程及临床状况。
Objective To investigate the rational use of antidote in AOPP. Methods A controlled study was conducted to divide the AOPP inpatients admitted from April 1998 to December 1998 into 20 patients in the treatment group and 20 in the control group respectively. On the basis of comprehensive medical treatment, the patients were divided into special antidotes. The treatment group early enough, repeated application of energy supplement small doses of atropine supplements, energy agents with 5-7 days; the control group by traditional methods using energy agents and atropine, energy agent for 3 days. Results Comparison of the two groups atropine, the amount of energy agent, the incidence of complications and hospital days were significantly different (P <0 01); no difference in the cure rate (P> 0 05), but the treatment group excellent clinical status In the control group. Conclusion The application of this program to treat AOPP can reduce the compound poisoning of atropine and effectively prevent and treat the intermediate syndrome, so as to change its natural course and clinical status.