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表皮生长因子 (epidermalgrowthfactor,EGF)是多肽家族中最早被发现的生长因子之一 ,Cohen等人于 6 0年代首先从小鼠颌下腺分离出一种蛋白 ,能使新生鼠提早睁眼和长出牙齿 ,由于组织上能使实验小鼠表皮成熟和生长 ,这种蛋白质被命名为表皮生长因子[1 ] 。由于EGF的发现及研究成
Epidermal growth factor (EGF) is one of the earliest discovered growth factors in the polypeptide family. Cohen et al. First isolated a protein from the mouse submandibular gland in the 1960s, enabling newborn rats to open their eyes earlier and grow their teeth. As the tissue matures and grows in the mouse epidermis, the protein is named epidermal growth factor [1]. Due to the discovery and research of EGF into