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在近年深入广泛研究缩小心肌梗塞范围的工作中,心率和血压的作用业已受到重视,其目的在于寻求心率和血压的最适水平,要求用药要注意剂量和时间。在以往的研究中,我们看到降低实验动物的心率20%或升高动脉血压10%,以及二者相结合,都具有减轻急性心肌缺血的作用。但是,动脉血压既是左心室的后负荷,血压升高会加大心肌耗氧量;而动脉血压又是冠脉灌注的动力。毫无疑问,对于急性心肌梗塞(AMI)患者必须有一个血压的
In recent years, in-depth study of the scope of narrowing the scope of myocardial infarction, the role of heart rate and blood pressure has been valued, its purpose is to seek the optimal level of heart rate and blood pressure, requiring medication to pay attention to dose and time. In previous studies, we saw that reducing heart rate by 20% in experimental animals or increasing arterial blood pressure by 10%, and the combination of the two, have the effect of reducing acute myocardial ischemia. However, arterial blood pressure is not only the left ventricular afterload, increased blood pressure will increase myocardial oxygen consumption; and arterial blood pressure is the driving force of coronary perfusion. There is no doubt that there must be a blood pressure in patients with acute myocardial infarction (AMI)