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长春宝由明代御医龚廷贤编著的《寿世保元》中“长春不老仙丹”化裁而成;以熟地、枸杞子、杜仲、牛膝、何首乌、寄生、女贞子、墨旱莲为主药;仙茅、淫羊藿、巴戟、补骨脂为辅药;以人参、黄芪、茯苓、山药、五味子、麦冬、当归、丹参为佐药;以知母、黄柏、天冬、生地黄为使药。注重补肝肾、益气血、调和阴阳而顾全面。动物药理实验观察一、对肾阴虚肾阳虚的影响长春宝能明显减轻小鼠肾阳虚模型的肾上腺萎缩状态,也能明显减轻小鼠肾阴虚模型的胸腺萎缩现象(表1,2)。提示本药对肾阳肾阴俱虚者有双向调节作用。
Changchun Bao was created from the “Changchun not elixir” in the “Shou Shi Bao Yuan” edited by the Ming Dynasty physician Gong Tingxian; with Rehmannia, Gardenia, Eucommia, Achyranthes, Polygonum multiflorum, Parasitoid, Ligustrum lucidum, and Eclipta prostrata as main medicines. Curcuma, Epimedium, Baba, Buguzhi as a supplement; Ginseng, Astragalus, Poria, Yams, Schisandra, Ophiopogon japonicus, Angelica, and Salvia miltiorrhiza as adjuvant; Anemarrhena, Phellodendron, Asparagus, Radix Rehmanniae For medicine. Pay attention to make up liver and kidney, benefit qi and blood, reconcile yin and yang while taking care of everything. Animal pharmacological experiment observation First, the effect of kidney yin deficiency kidney yang deficiency Changchun Bao can significantly reduce the adrenal atrophy state of the mouse kidney yang deficiency model, but also can significantly reduce the thymus atrophy in the mouse kidney yin deficiency model (Table 1, 2 ). It indicates that the drug has a two-way regulatory effect on kidney yang and yin deficiency.