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恶性浸润和无限制增生是恶性肿瘤细胞生物学行为的两大特征,常被作为区别肿瘤良、恶性的重要标志,多年来已受到细胞生物学家和临床学家所重视。近年,国外运用组织培养术对人体和动物某些肿瘤的体外浸润曾做了一些工作,虽然有个别观察结肠癌肝转移标本的体外浸润,但是,对于人体肝癌的类似研究,迄今文献上尚未见报道。现就我们对人体肝癌细胞系与鸡胚中肾器官联合培养的实验结果报道于下。
Malignant infiltration and unrestrained proliferation are two major features of the biological behavior of malignant tumor cells, and are often used as important markers for distinguishing benign and malignant tumors. Over the years, they have been valued by cell biologists and clinical scientists. In recent years, the use of tissue culture abroad has done some work on the in vitro infiltration of certain human and animal tumors. Although there are individual observations of in vitro infiltration of colon cancer liver metastases, similar studies on human liver cancer have not been found in the literature to date. Reported. Now we report on the experimental results of our co-cultivation of human hepatoma cell lines and chicken embryo kidney organ.