论文部分内容阅读
报道了以 [TbAs4 W4 0 O14 0 ]2 5- 及 [PrSb9W2 1O86]16- 为代表的穴状稀土杂多阴离子的体外、体内抗肿瘤活性及体内抗RauscherMuLV和LP BM5MuLV病毒活性。以上化合物对H2 2 ,B16,HL 60及活体直肠癌、乳腺癌细胞有抑制作用 ,能减轻荷瘤鼠的瘤重及延长其存活时间及荷病毒鼠的脾重。
In vitro and in vivo antitumor activities of the cryptate rare earth heteropolyanions represented by [TbAs4 W40 014 0] 2 5- and [PrSb9W2 1O86] 16- are reported, as well as in vivo anti-RauscherMuLV and LP BM5MuLV virus activity. The above compounds have inhibitory effect on H2 2, B16, HL60 and living rectum cancer and breast cancer cells, can reduce tumor weight of tumor-bearing mice and prolong their survival time and spleen weight of mice infected with virus.