本文发现,吡喹酮致家兔心律失常作用存在光学异构体的特异性。iv吡喹酮或其异构体46mg/kg后,家兔心率减慢,并诱发各种类型的心律失常和其它ECG政变。异位节律总发率以右旋吡喹酮组最高,占100％,性质亦最为严重,左旋组最低,占20％,两者有非常显著差异(P<0.01);消旋组介于二者之间,古60％。减慢心率作用亦以右旋体最强,左旋 This paper found that praziquantel induced rabbit arrhythmia specificity of optical isomers. After praziquantel or its isomer at 46 mg / kg, rabbits have a slow heart rate and induce various types of arrhythmias and other ECG coups. The total incidence of ectopic rhythm was the highest in praziquantel group, accounting for 100%, the most serious in nature, the lowest in left-handed group, accounting for 20% (P <0.01) Between, ancient 60%. Slow down the role of heart rate is the strongest right-handed, left-handed