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目的:了解某院胸外科恶性肿瘤患者化疗药物的使用现状及合理性。方法:对某院2008-2010年接受全身化疗的恶性肿瘤患者化疗药物的使用情况及合理性进行回顾性统计、分析。结果:纳入研究的恶性肿瘤患者共计112人,412例次化疗方案。在861条化疗药物医嘱中,医嘱不合格率为30.0%,不合理用药现象主要表现为顺铂的给药剂量不足,卡铂的溶媒选择不当,以及化疗药物的给药浓度、给药顺序、化疗前预处理不当等。结论:该院胸外科恶性肿瘤患者化疗药物基本合理,但在部分药物的具体应用上,仍存在一定的不足,在今后的临床应用中仍有待改进。
Objective: To understand the status and rationality of chemotherapy in patients with malignant tumor of thoracic surgery in a hospital. Methods: Retrospective statistics and analysis were made on the use and rationality of chemotherapy drugs in patients with malignant tumor undergoing systemic chemotherapy during 2008-2010 in a hospital. RESULTS: A total of 112 patients with malignant tumors were included in the study, with 412 chemotherapy regimens. In the 861 chemotherapy drug orders, the doctor’s order failed rate of 30.0%, irrational drug use mainly for the lack of cisplatin dose, inappropriate selection of carboplatin solvent, and the concentration of drug delivery, drug administration sequence, Pre-treatment before chemotherapy and so on. Conclusion: The chemotherapeutic drugs in patients with thoracic malignant tumors in this hospital are basically reasonable. However, there are still some shortcomings in the specific application of some drugs, and they still need to be improved in the future clinical application.