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姜黄素是从姜黄根茎中提取的一种植物多酚,来源广泛,价格低廉,药理作用广泛。其抗肿瘤作用机制主要是诱导肿瘤细胞凋亡,阻断肿瘤细胞的生长的信号传导通路,抑制肿瘤血管生成及调节肿瘤细胞黏附分子的表达。本文综述其抗肿瘤作用机制。
Curcumin is a kind of plant polyphenols extracted from the rhizome of curcuma longa and has a wide range of sources and low cost. The anti-tumor mechanism is mainly induced tumor cell apoptosis, blocking the growth of tumor cells signal transduction pathway, inhibition of tumor angiogenesis and regulation of tumor cell adhesion molecule expression. This article reviews its antitumor mechanism.