论文部分内容阅读
目前我国糖尿病及恶性肿瘤的发病率都在逐年增加,同时有资料显示糖尿病患者的恶性肿瘤发病率比非糖尿病患者的发病率更高。而恶性肿瘤的发生本质上是由于原癌基因的激活和抑癌基因的失活所致。本文就目前国内外对癌基因与抑癌基因参与糖尿病的发病机制的相关研究进展进行综述。
At present, the incidence of diabetes mellitus and malignant tumors in our country are increasing year by year. At the same time, some data show that the incidence of malignant tumors in diabetic patients is higher than that in non-diabetic patients. The occurrence of malignant tumors is essentially due to the activation of protooncogene and the inactivation of tumor suppressor gene. This review summarizes the current research progress on the mechanisms of oncogenes and tumor suppressor genes participating in the pathogenesis of diabetes in our country.