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目的：观察患者综合护理干预下的护理效果，分析综合护理干预对微创颅内血肿清除术的辅助作用。方法：选择我院符合条件的高血压脑出血患者 186 例，根据患者就诊顺序的单双号分为试验组和对照组，各 93 例，试验组在对照组基础上加用综合护理干预，对照组则利用传统护理，观察两组患者的差异，分析护理工作对患者等方面的影响。结果：试验组各项护理指标高于对照组，差异显著(P＜0.05)。结论：对患者进行微创颅内血肿清除术治疗效果较好，同时利用综合护理干预开展辅助护理，能够显著提高患者的康复效果，避免患者不良事件发生，值得临床重视。“,”Objective: To observe the nursing effect of comprehensive nursing intervention on patients, and analyze the auxiliary effect of comprehensive nursing intervention on minimally invasive intracranial hematoma removal. Methods: 186 patients with hypertensive intracerebral hemorrhage in our hospital were selected and divided into the experimental group and the control group according to the single or even number of patients' visiting order, 93 cases in each group. The experimental group was given comprehensive nursing intervention on the basis of the control group, while the control group was using traditional nursing care to observe the differences between the two groups and analyze the influence of nursing work on patients. Results: the nursing indexes of the experimental group were higher than those of the control group (P < 0.05). Conclusion: the effect of minimally invasive intracranial hematoma removal is better, and comprehensive nursing intervention can significantly improve the rehabilitation effect ofpatients and avoid the occurrence of adverse events, which is worthy of clinical attention.