各种肾脏疾病有不同特征和形式的细胞增生,而近年研究表明各种生理病理因素最终的共同途径将作用于细胞周期,通过对参与细胞周期特异性调节蛋白的影响决定其结局(肥大、凋亡、增殖或分化)。探讨其在各种肾脏疾病病理过程中的作用,对此深入研究可为肾脏疾病的防治提供新的启示。 Various renal diseases have different characteristics and forms of cell proliferation, and recent studies have shown that the ultimate common pathway of various physiological and pathological factors will act on the cell cycle, and its outcome will be determined by its involvement in cell cycle-specific regulatory proteins (hypertrophy, apoptosis Death, proliferation or differentiation). Explore its role in the pathological process of various kidney diseases, and in-depth study can provide new insights into the prevention and treatment of kidney disease.