新型隐球菌感染继发于肝硬化者临床少见,我院遇到1例肝硬化并发新型隐球菌性脑膜炎(简称隐脑),现报告如下。 患者男,50岁。因反复腹胀、黄疸、浮肿3年余,两前额持续性胀痛、发热20天入院。患者半年前因十二指肠溃疡穿孔手术,术中及病理检查发现有肝硬化,术后长期服护肝、利尿药治疗。体检:体温39℃,脉搏98次/分,呼吸22次/分,血压19.7/10.7KPa。神志清楚,面色晦暗,皮肤巩膜轻度黄染。胸部见7颗蜘蛛痣,并有肝掌。颈部抵抗感,心肺(-)。腹隆起,上腹部见6Cm长的手术疤痕,肝未触及,脾左助下2Cm,质偏硬,腹水征(+),双下肢浮肿,双克氏征(+)。实验室 Cryptococcus neoformans secondary to cirrhosis of the clinical rare, I met 1 case of cirrhosis of the liver with cryptococcal meningitis (referred to as crypto), are as follows. Male patient, 50 years old. Due to repeated abdominal distension, jaundice, edema more than 3 years, the two forehead persistent pain, fever 20 days admitted. Patients with duodenal ulcer perforation surgery six months ago, intraoperative and pathological examination found cirrhosis, long-term treatment of liver, diuretic treatment. Physical examination: body temperature 39 ℃, pulse 98 beats / min, breathing 22 beats / min, blood pressure 19.7 / 10.7KPa. Conscious, dark complexion, skin scleral mild yellow dye. See seven spider nevus chest, and liver palms. Neck resistance, cardiopulmonary (-). Abdominal uplift, see the 6Cm long surgical scar in the upper abdomen, the liver is not touched, left spleen 2Cm, qualitative hard, ascites (+), both lower extremity edema, double Keshi sign (+). laboratory