将１９９６年１月获得的１例乳腺浸润性导管癌患者的原发肿瘤和转移淋巴结，移植于ＢＡＬＢ／ｃ－ｎｕ／ｎｕ裸小鼠胸部乳垫下，３１天后在局部出现肿瘤结节，并逐渐长大，以后进行鼠间传代移植，现已１５代，移植成功率１００％，肿瘤保持了原先的生物学特性。经医学文献检索证实，该模型在国内属首次建立，为乳腺癌的深入研究建立了一个很有价值的模型。 Primary tumors and metastatic lymph nodes of a patient with breast invasive ductal carcinoma obtained in January 1996 were transplanted under the breast pad of BALB/c-nu/nu nude mice, and tumor nodules appeared locally after 31 days. Gradually grew up, and then it was transplanted between mice. Now it has been 15 generations, the success rate of transplantation is 100%, and the tumor has maintained its original biological characteristics. The medical literature search confirmed that the model was established for the first time in China and established a valuable model for the in-depth study of breast cancer.