前言 莫达非尼(Modafinil)是一种警觉性物质,已被认为比苯丙胺更安全而副作用显然较少。虽然,莫达非尼已用于对抗军事上的疲劳(如海湾战争),但它对长时工作,丧失睡眠期间产生的智能减退的改善能力如何,人们了解甚少。方法 34名军人受试者,在持续64h无睡眠状态下,进行一组智能和自我评估试验(12名服用莫达非尼300mg;11名服D-苯丙胺20 Introduction Modafinil is a vigilant substance that has been considered safer than amphetamines with significantly fewer side effects. Although modafinil has been used to combat military fatigue (such as the Gulf War), little is known about how much it modifies the ability to improve long-term work, loss of intellectual decline during sleep loss. Methods Thirty-four military subjects underwent a series of intelligence and self-assessment tests (12 taking modafinil 300 mg; 11 taking D-amphetamine 20