发现导致白血病前期状态——5q-综合征的原因可能已为期不远了。该综合征在老年妇女中最常见,某些血细胞含量缺失,而其它细胞数量则增加,最终会发展成急性白血病。此综合征的特征和名称均源于第5号染色体q区段基因缺失。急性髓性白血病中也有类似的染色体异常。Huebner等发现一种生长因子[粒细胞-巨噬细胞集落刺激因 The cause of the discovery of the pre-leukemic state, the 5q-syndrome, may not be far behind. The syndrome is most common in older women. Some blood cell levels are absent, while other cells increase in number and eventually develop into acute leukemia. The characteristics and name of this syndrome are all derived from the loss of q segment gene on chromosome 5. There are similar chromosomal abnormalities in acute myeloid leukemia. Huebner et al. found a growth factor [granulocyte-macrophage colony stimuli