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从接种口服脊髓灰质炎疫苗后约 1 2周的 1名 2岁男孩的粪便标本中分离到Sabin3/Sabin2 /Sabin3( S3/2 /3)型间重组脊髓灰质炎病毒。 由于该分离株的初步鉴定为嵌合 Sabin3/Sabin2核壳结构 ;从而使作者进一步研究了这个病毒的整个基因组序列、抗原特性和温度敏感性。 研究
The Sabin3 / Sabin2 / Sabin3 (S3 / 2/3) type of recombinant poliovirus was isolated from stool specimens of a 2-year-old boy about 12 weeks after oral polio vaccine immunization. Because of the initial identification of this isolate as a chimeric Sabin3 / Sabin2 core-shell structure, the authors further investigated the entire genome sequence, antigenicity, and temperature sensitivity of this virus. the study