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目的了解和分析2010年我院抗菌药物不良反应情况,为临床合理、安全用药提供依据。方法汇总2010年收集到的抗菌药物不良反应报告,按药物不良反应因果关系判断标准进行分析、评价、分级、统计。结果抗菌药物不良反应报告共计188例,排名前三位的分别是头孢菌素类药物(29.647%)、喹诺酮类药物(22.22%)、青霉素类(22.22%)。结论抗菌药物不良反应与药物性质、临床使用量、个体因素等密切相关。
Objective To understand and analyze the adverse reactions of antimicrobial agents in our hospital in 2010 and provide the basis for clinical rational and safe drug use. Methods The reports of adverse reactions of antimicrobial agents collected in 2010 were summarized and analyzed, evaluated, graded and statistically analyzed according to the causality of adverse drug reactions. Results A total of 188 reports of adverse reactions of antimicrobial agents were reported. The top three were cephalosporins (29.647%), quinolones (22.22%) and penicillins (22.22%). Conclusion The adverse reactions of antibiotics are closely related to the nature of drugs, clinical usage, individual factors and so on.