论文部分内容阅读
δ肝炎病毒(HDV)具有高度致病性,可引起急、慢性肝病。以往临床研究提示,HDV 感染与慢性乙型肝炎病毒(HBV)携带者的严重性肝病有关。作者在大量罹患慢性肝病的 HBsAg 持续阳性患者中研究了HDV 感染的发生率和临床意义。对这些患者平均随访了5年,报道了 HDV 阳性的慢性肝病的主要临床和实验室结果,并将HDV 阳性患者的特征与 HDV 阴性患者和慢性乙型肝炎患者作了比较。
The hepatitis C virus (HDV) is highly pathogenic and can cause acute and chronic liver disease. Previous clinical studies suggest that HDV infection is associated with severe liver disease in carriers of chronic hepatitis B (HBV). The authors studied the incidence of HDV infection and its clinical significance in patients with persistent HBsAg persistence in a large number of patients with chronic liver disease. These patients were followed for an average of 5 years. The main clinical and laboratory findings of HDV-positive chronic liver disease were reported and the characteristics of HDV-positive patients were compared with HDV-negative patients and chronic hepatitis B patients.