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目的探讨颈内动脉闭塞的相关危险因素。方法回顾性分析2003年1月~2008年3月北京友谊医院收治的94例颈内动脉闭塞患者的危险因素,并与2007年1月~2007年6月收治的105例(无颈内动脉闭塞)缺血性脑血管病患者(对照组)的危险因素进行比较,并进行多因素Logistic回归分析。结果2组间缺血性脑血管病常见的危险因素如高血压病、高脂血症、糖尿病、高龄和饮酒史,无统计学差异(P>0.05),而性别、脑卒中病史及吸烟史3个因素在2组间具有统计学意义(P<0.05)。将男性、脑卒中病史及吸烟史3个变量代入Logistic回归方程行多因素分析显示,3种相关危险因素中性别与颈内动脉闭塞相关性最高(P=0.041),吸烟史和脑卒中病史为仅次于性别的危险因素。结论性别、脑卒中病史及吸烟史是颈内动脉闭塞的重要相关危险因素,临床应加强脑卒中的二级预防,并加强戒烟宣传等工作。
Objective To explore the related risk factors of internal carotid artery occlusion. Methods The clinical data of 94 patients with internal carotid artery occlusion admitted to Beijing Friendship Hospital from January 2003 to March 2008 were retrospectively analyzed. The clinical data of 105 patients with internal carotid artery occlusion ) Patients with ischemic cerebrovascular disease (control group) were compared, and multivariate logistic regression analysis was performed. Results There were no significant differences in the common risk factors of hypertension, hyperlipidemia, diabetes, advanced age and alcohol consumption between the two groups (P> 0.05), while the prevalence of gender, stroke and smoking history Three factors were statistically significant between the two groups (P <0.05). Multivariate analysis showed that among the three risk factors, the correlation between sex and internal carotid artery occlusion was the highest (P = 0.041), smoking history and stroke history were Second only to gender risk factors. Conclusions Gender, history of stroke and smoking history are important risk factors for ICA occlusion. Secondary prevention of stroke should be strengthened and smoking cessation and publicity should be strengthened.