慢性肝性脑病(CHE)发病机制的研究虽有显著进展,但对之仍不清楚.由于对中枢神经系统正常机能调节的知识尚不完整,对维持正常意识的大脑特定区域的代谢变化缺乏精确的测定技术,因而要弄清CHE的病理生理学非常困难.近年的研究主要集中在肝功能不全时脑内氨基酸代谢产生的脑毒物(氨、酶、硫醇)及 Although there has been significant progress in the pathogenesis of chronic hepatic encephalopathy (CHE), its lack of knowledge of the normal functional modulation of the central nervous system remains unclear for the metabolic changes in specific areas of the brain that maintain normal awareness Of the determination of the technology, and therefore to understand the pathophysiology of CHE is very difficult.In recent years, the study focused on hepatic dysfunction brain amino acids metabolism (ammonia, enzymes, thiols) and