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临床上脑缺血后白质损伤十分常见 ,并已引起人们广泛重视。脑缺血后的白质保护是当前神经药理发展的方向之一 ,并由此提出了脑缺血后全脑保护的概念。脑白质缺血性损伤的动物模型和组织学定量评价方法现已建立 ,其缺血易损的机制将逐步阐明 ,相关的药物保护措施将会补充或替代当前脑缺血的治疗方法
After clinical cerebral ischemia white matter damage is very common and has caused widespread attention. White matter protection after cerebral ischemia is one of the current directions of neuropsychopharmacology, and thus put forward the concept of global brain protection after cerebral ischemia. Animal model of cerebral white matter ischemic injury and quantitative evaluation of histological methods have been established, the mechanism of its vulnerability to ischemia will gradually clarify the relevant drug protection measures will complement or replace the current treatment of cerebral ischemia