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目的:观察中西医结合干预原发开角型青光眼的临床疗效。方法:选取原发性开角型青光眼78例,给予曲伏前列素滴眼液和辨证给予不同的中药进行综合干预,观察视力、视野及视诱发电位的改善情况。结果:治疗前患者中最好视力为0.5(伴有屈光不正患者以矫正视力为准),治疗后患者视力显效者28例,有效者44例,无效者6例,有效率为92.3%;治疗后患者视野的平均光敏度、平均缺损均较治疗前有所改善(P<0.05);治疗后视诱发电位的振幅及潜伏期与治疗前比较,改善明显(P<0.05)。结论:中西医结合综合干预原发开角型青光眼疗效较佳,可临床推广应用。
Objective: To observe the clinical effect of integrated traditional Chinese and western medicine on primary open angle glaucoma. Methods: Seventy-eight patients with primary open-angle glaucoma were selected and treated with travoprost eyedrops and different TCMs. The visual acuity, visual field and visual evoked potentials were observed. Results: The best visual acuity before treatment was 0.5 (with corrected visual acuity in patients with ametropia). After treatment, 28 patients with visual acuity were effective, 44 were effective and 6 were ineffective. The effective rate was 92.3%. After treatment, the average photosensitivity and average defect in patients’ fields were significantly improved compared with those before treatment (P <0.05). After treatment, the amplitude and latency of visual evoked potential were significantly improved (P <0.05). Conclusion: The combination of traditional Chinese and Western medicine comprehensive primary open angle glaucoma better efficacy, clinical application.