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目的:探讨补肾固齿丸联合盐酸米诺环素软膏治疗重度慢性牙周炎的临床疗效。方法:80例重度慢性牙周炎的患者随机分为2组,每组40例。对照组采用盐酸米诺环素软膏治疗;观察组采用补肾固齿丸联合盐酸米诺环素软膏治疗。分别观察两组的中医症候疗效和牙周临床指标改善情况。结果:观察组总有效率95.00%高于对照组77.50%(P<0.05)。治疗3、6个月,观察组PD、PAL、BI和牙槽骨密度改善优于对照组(P<0.05)。结论:补肾固齿丸联合盐酸米诺环素软膏治疗重度慢性牙周炎具有较好的疗效。
Objective: To investigate the clinical effect of Bushen Guotai Pills combined with Minocycline Hydrochloride Ointment in the treatment of severe chronic periodontitis. Methods: Eighty patients with severe chronic periodontitis were randomly divided into two groups, 40 cases in each group. The control group was treated with minocycline hydrochloride ointment. The observation group was treated with Bushen Guotai Pill combined with minocycline hydrochloride ointment. The curative effect of traditional Chinese medicine and the improvement of periodontal clinical indexes of the two groups were observed. Results: The total effective rate in observation group was 95.00% higher than that in control group (77.50%, P <0.05). At 3 and 6 months after treatment, the improvement of PD, PAL, BI and alveolar bone density in the observation group was better than that in the control group (P <0.05). Conclusion: Bushen Guotai Pill combined with Minocycline Hydrochloride Ointment has a good curative effect on severe chronic periodontitis.