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目的观察初诊2型糖尿病患者尿白蛋白排泄率(UAER)与早期血管动脉硬化的关系。方法对86例初诊2型糖尿病患者,留尿测定尿UAER,并根据UAER分为两组,同时用高分辨率超声检测颈动脉内膜厚度(IMT),进行组间比较,对两者关系进行统计分析。结果初诊2型糖尿病患者颈动脉IMT与尿UAER、高敏C反应蛋白(hs-CRP)显著相关。结论尿UAER增高是初诊2型糖尿病患者早期大血管病变的独立危险因素。
Objective To observe the relationship between urinary albumin excretion rate (UAER) and early vascular atherosclerosis in newly diagnosed type 2 diabetic patients. Methods Urine UAER was measured in urine of 86 newly diagnosed type 2 diabetic patients and divided into two groups according to UAER. The carotid intima-media thickness (IMT) was measured by high-resolution ultrasonography and the relationship between the two groups was compared Statistical Analysis. Results Carotid IMT was significantly associated with urinary UAER and hs-CRP in newly diagnosed type 2 diabetic patients. Conclusion The increased urinary UAER is an independent risk factor for early macrovascular disease in newly diagnosed type 2 diabetic patients.