近年来,关于新生儿尤其早产儿肺部疾病发病率及死亡率高的现象已引起广泛关注,但其发病早期呼吸道症状和体征不明显,早期诊断和治疗仍存在困难。Clara细胞分泌蛋白(clara cell secretory protein,CCSP)主要由细支气管、终末细支气管及呼吸性细支气管上的Clara细胞分泌产生,具有抗炎、 In recent years, the incidence of lung diseases in neonates, especially premature infants and morbidity and mortality have attracted widespread attention, but the early onset of respiratory symptoms and signs are not obvious, early diagnosis and treatment are still difficult. Clara cell secretory protein (Clara cell secretory protein, CCSP) mainly by the bronchioles, terminal bronchioles and respiratory bronchial Clara cells produce secreted, with anti-inflammatory,