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目的初步探讨MR扩散加权成像对甲状腺良恶性结节诊断的价值。方法收集2014年1月至2015年4月在我院就诊的甲状腺结节病人42例及健康志愿者20例,采用平面回波成像(EPI)技术,对42例甲状腺局灶性病变(良性组22例、恶性组20例)行DWI检查,测量b值取400 s/mm2时良恶性结节的信号强度和ADC值,并比较良恶性组之间的差异。所有病例均经手术病理活检证实。结果甲状腺良、恶性结节在b值为400 s/mm2时的ADC值分别为(2.5309±0.18878)×10-3 mm2/s和(1.5495±0.16972)×10-3 mm2/s;甲状腺良性结节的ADC值要高于恶性结节的ADC值,二者差异有统计学意义(P<0.05)。正常甲状腺组织ADC值与患甲状腺结节疾病患者的正常甲状腺组织的ADC值无明显差异(P>0.05)。结论良性结节的ADC值高于恶性结节的ADC值,MR扩散加权成像有助于甲状腺良恶性结节诊断及鉴别诊断。
Objective To investigate the value of MR diffusion weighted imaging in the diagnosis of benign and malignant thyroid nodules. Methods Forty-two patients with thyroid nodules and 20 healthy volunteers were enrolled in our hospital from January 2014 to April 2015. Plane echo imaging (EPI) 22 cases, 20 cases of malignant group) underwent DWI examination. The signal intensity and ADC value of benign and malignant nodules with b value of 400 s / mm2 were measured, and the differences between benign and malignant groups were compared. All cases were confirmed by pathological biopsy. Results The ADC values of benign and malignant thyroid nodules were (2.5309 ± 0.18878) × 10-3 mm2 / s and (1.5495 ± 0.16972) × 10-3 mm2 / s when the b value was 400 s / mm2 respectively. The benign thyroid gland The ADC value of the section was higher than the ADC value of malignant nodules, the difference was statistically significant (P <0.05). There was no significant difference in ADC value between normal thyroid tissue and normal thyroid tissue in patients with thyroid nodules (P> 0.05). Conclusions The ADC value of benign nodules is higher than that of malignant nodules. MR diffusion weighted imaging is helpful for the diagnosis and differential diagnosis of benign and malignant thyroid nodules.