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例1,男,61岁,住院号25648,诊断:肺Ⅲ上中/上中下涂(一),进展期,85年5月30日给异烟肼(INH)0.3,利福定(RFD)0.15和乙胺丁醇(EMB)0.75,均为qd口服,20d(天)后开始出现全身皮肤瘙痒,可触及针头大小之皮疹,疹色同正常皮肤,同时两乳房逐渐增大,3mo(月)后,乳房如鸡蛋大、质软,肤色正常,有触痛,挤捏无乳汁流出.皮疹经口服苯海拉明、异丙嗪、葡萄糖酸钙、扑尔敏、赛庚啶,静注葡萄糖酸钙和外搽炉甘石洗剂等治疗无效.9月30日停用RFD,其他药物治疗继续
Case 1, male, 61 years old, hospital number 25648, diagnosis: pulmonary Ⅲ upper / middle to upper smear (I), the progress of the May 30, 85 to isoniazid (INH) 0.3, rifamycin (RFD ) 0.15 and ethambutol (EMB) 0.75, all qd orally, 20d (days) began to appear systemic pruritus, can reach the size of the needle rash, rash with normal skin, while the two breasts gradually increased, 3mo Month), the breasts, such as large eggs, soft, normal color, tenderness, crowded squeeze no latex out.The rash oral diphenhydramine, promethazine, calcium gluconate, chlorpheniramine, cyproheptadine, Note Calcium gluconate and external application of calamine lotion and other treatment ineffective. September 30 disable RFD, other drug treatment continues