胃粘膜表面粘液细胞合成的胃粘蛋白呈浓聚状态,当粘液细胞受到刺激时,粘液颗粒以胞吐作用、顶浆分泌、全浆分泌三种方式分泌到胃粘膜表面。局部机械刺激、迷走神经的紧张和五肽促胃液素、胆囊收缩素等神经体液因子可促进胃粘液的合成与分泌,而皮质激素、非甾体抗炎药可抑制和破坏其作用。 Gastric mucosa mucus cells synthesized gastric mucin protein was concentrated state, when the mucous cells are stimulated, mucus granules to exocytosis, apocrine secretion, whole plasma secretion of three ways to the gastric mucosal surface. Local mechanical stimulation, vagal nerve tension and pentapeptide gastrin, cholecystokinin and other neurohumoral factors can promote gastric mucus synthesis and secretion, and corticosteroids, non-steroidal anti-inflammatory drugs can inhibit and destroy its role.