本文报告了23例新生儿缺氧缺血性脑病（HIE）合并低钙血症，临床具有NIE表现又伴有面部和肢体不规则、不固定的节律性抽动、眼球凝视、震颤和有呼吸暂停及血钙下降等症状和体征。研究发现新生儿低钙血症的发生不取决于缺氧程度，而取决于缺氧的时间。23例均使用葡萄糖酸钙治疗，结果表明及时补钙对提高新生儿存活质量有一定价值。 This article reports 23 cases of neonatal hypoxic-ischemic encephalopathy (HIE) with hypocalcemia, clinical manifestations of NIE also accompanied by facial and limb irregular, irregular rhythmic twitch, eye gaze, tremor and apnea And calcium and other symptoms and signs of decline. The study found that neonatal hypocalcemia does not depend on the occurrence of hypoxia, but on the time of hypoxia. 23 cases were treated with calcium gluconate, the results show that timely calcium to improve the quality of life of newborns have some value.