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近几年来,由于肺结核治疗不当,空洞长期不愈,空洞壁增厚,病灶出现广泛纤维化;随机体免疫力的高低波动,病灶吸收、修复与恶化、进展交替发生,成为慢性纤维空洞型肺结核,甚至出现耐药结核病的症状[1]。国内外相关领域的专家学者研究发现[2],左氧氟沙星联合异烟肼已逐渐应用于预防和治疗耐药结核病。据国内外流行病学研究发现[3],规律采用左氧氟沙星联合异烟肼可使患耐药结核病的风险降低。耐药结核病其发病机
In recent years, due to improper treatment of tuberculosis, empty long-term unhealed, cavity wall thickened, the lesions appear extensive fibrosis; fluctuations in the level of the body immunity, lesion absorption, repair and deterioration, the progress alternately, as chronic fibrous hollow tuberculosis , And even the symptoms of drug-resistant tuberculosis [1]. Experts and scholars in related fields at home and abroad have found [2] that levofloxacin and isoniazid have been gradually applied in the prevention and treatment of drug-resistant tuberculosis. According to epidemiological studies at home and abroad found [3], the law of levofloxacin combined with isoniazid can reduce the risk of drug-resistant tuberculosis. Drug-resistant tuberculosis pathogenesis