论文部分内容阅读
以往的研究显示马来丝虫微丝蚴主要诱导Th1型细胞因子的产生 ,体外一氧化氮(NO)能够介导微丝蚴的死亡。本研究提出了快速清除 (CBA/Ca)和缓慢清除 (C57BL/6 )小鼠产生的γ干扰素 (IFN γ)对清除微丝蚴的作用。给 6 - 8周雄性鼠 (CBA/Ca鼠和C57BL/6鼠 )尾静脉注射 2× 1 0 5微丝
Previous studies have shown that microfilaria malayi mainly induces the production of Th1-type cytokines, and nitric oxide (NO) in vitro can mediate the death of microfilariae. This study proposed the effect of interferon gamma (IFNγ) produced by the rapid clearance (CBA / Ca) and slow clearance (C57BL / 6) mice on the clearance of microfilariae. Male 6-week-old male mice (CBA / Ca and C57BL / 6 mice) were injected with 2 × 10 5 microfilaments