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目的观察亚低温治疗重型颅脑损伤的临床效果。方法选取重型颅脑损伤患者92例为研究对象,随机分为观察组和对照组,每组46例。对照组采用手术降低颅压治疗和常规药物治疗,观察组在此基础上采用亚低温治疗。观察2组颅内压、血糖数值及预后情况。结果 2组治疗后颅内压、血糖数值均低于治疗前,且观察组低于对照组(P<0.05);随访2~6个月后,观察组预后效果优于对照组(P<0.05)。结论亚低温治疗重型颅脑损伤可降低颅内压,且有效改善患者预后,值得临床推广应用。
Objective To observe the clinical effect of mild hypothermia on severe craniocerebral injury. Methods Ninety-two patients with severe traumatic brain injury were selected as study subjects and randomly divided into observation group and control group with 46 cases in each group. The control group was treated with intracranial pressure to reduce the intracranial pressure and conventional drug treatment. On the basis of this, the observation group was treated with mild hypothermia. Intracranial pressure, blood glucose and prognosis were observed in two groups. Results The intracranial pressure and blood glucose of two groups after treatment were lower than those before treatment, and the observation group was lower than that of the control group (P <0.05). The prognosis of the observation group was better than that of the control group after 2 to 6 months follow-up (P <0.05) ). Conclusion Mild hypothermia treatment of severe craniocerebral injury can reduce intracranial pressure, and effectively improve the prognosis of patients, worthy of clinical application.