论文部分内容阅读
目的比较单独使用153Sm-EDTMP与153Sm-EDTMP联合“云克”(99Tc-MDP)两种方法治疗多发性骨转移瘤的止痛效果及转移灶效果。方法96例确诊为多发性骨转移肿瘤中,60例单独使用153Sm-EDTMP治疗,36例使用153Sm-EDTMP联合“云克”治疗,比较两种方法的治疗效果。结果单独使用153Sm-EDTMP治疗,缓解骨痛的总有效率为61.67%,转移灶消除或缩小的总有效率为20.00%,而153Sm-EDTMP与“云克”联合治疗则分别为88.89%和44.44%,两组间比较差异有高度显著性(P均<0.01)。结论单独使用153Sm-EDTMP治疗和153Sm-EDTMP联合“云克”治疗多发性骨转移瘤都是有效的止痛方法,但153Sm-EDTMP联合“云克”对于多发性骨转移瘤止痛效果更佳(88.89%),同时使部分转移灶完全消失、缩小或减少。
Objective To compare the analgesic effect and metastasis effect of 153Sm-EDTMP with 153Sm-EDTMP combined with “Yunke” (99Tc-MDP) in the treatment of multiple bone metastases. Methods Ninety-six patients were diagnosed as multiple bone metastases, 60 patients treated with 153Sm-EDTMP alone and 36 patients treated with 153Sm-EDTMP combined with “Yunke”. The therapeutic effects of the two methods were compared. Results With 153Sm-EDTMP alone, the total effective rate of relieving bone pain was 61.67%, the total effective rate of removing or reducing metastases was 20.00%, while the combination of 153Sm-EDTMP and Yunke was 88.89% and 44.44 respectively %, The difference between the two groups was highly significant (P all <0.01). Conclusion 153Sm-EDTMP and 153Sm-EDTMP combined with “Yunke” are effective analgesic methods for treating multiple bone metastases, but 153Sm-EDTMP combined with “Yunke” has better analgesic effect on multiple bone metastases (88.89 %), While part of the metastasis completely disappeared, reduced or reduced.