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白内障术后即行地塞米松和庆大霉素球结膜下注射,通常用以预防术后细菌感染及抑制炎症。实践证明,此法对降低白内障术后眼内炎的发生率是有效的。但皮质类固醇系免疫抑制剂,在理论上对术后感染性眼内炎有促进作用。为此,作者等做了动物实验,研究了地塞米松对庆大霉素预防兔人工晶体植入眼细菌性眼内炎的效果。20只体重2~3公斤的荷兰兔,右眼行晶体囊外摘出联合后房型人工晶体植入。缝合切口后,经角膜切口于前房注入0.1ml含5万金黄色葡萄球菌的接种物。此接种物的细菌数用次代培养证实100%能引起家兔眼内
Subconjunctival injection of dexamethasone and gentamicin is performed after cataract surgery and is usually used to prevent postoperative bacterial infections and suppress inflammation. Practice has proved that this method to reduce the incidence of endophthalmitis after cataract surgery is effective. However, corticosteroid immunosuppressive agents, in theory, postoperative infectious endophthalmitis have a role in promoting. To this end, the author did animal experiments to study the effect of dexamethasone gentamicin prophylactic rabbit intraocular lens implantation ocular bacterial endophthalmitis. 20 Dutch rabbits weighing 2 to 3 kg, extracapsular lens extraction in the right eye combined with posterior chamber intraocular lens implantation. After the incision was incised, 0.1 ml of the inoculum containing 50 000 Staphylococcus aureus was injected into the anterior chamber through the corneal incision. This inoculum bacterium number proved 100% with secondary culture can cause rabbits intraocular