论文部分内容阅读
药物性肝损害是药物治疗过程中的毒副作用之一,其临床表现多类似于中医所说的肝郁气滞兼挟湿热瘀血症。 病例介绍 患者男,24岁,木工。因畏寒、头痛,服用市售的新速效伤风胶囊(浙扛金华第二制药厂,批号:910111)两粒(超出产品说明书剂量1粒)自觉症状稍有改善,并于当日中午饮酒少许,再服该药两粒,次日晨,患者出现食欲不振、恶心、呕吐、疲乏,排浓茶色尿,随即就医。体检:发热、巩膜黄染、皮疹,肝在右肋下1.5cm,有明显的叩压痛感。舌暗红,苔黄腻,脉弦。化验室检查:谷丙转氨酶210单位,血清碱性磷酸酶42金氏单位/100ml,血清黄疸指数38单位,HBsAg阴性,患者及家族无肝炎史。遂确诊为药物性肝损害。中医认为属肝郁气
Drug-induced liver damage is one of the toxic side effects of the drug treatment process, its clinical manifestations are more similar to the traditional Chinese medicine said liver qi stagnation and damp-heat stasis. Case description Male patient, 24 years old, carpentry. Due to chills, headache, take a commercial new quick-acting Shangfeng Capsule (Zhejiang Jinhua second pharmaceutical factory, lot number: 910111) two (beyond the product manual dose 1) slight improvement in symptoms, and drink a little at noon on the day, Take the drug and then two tablets, the next morning, patients with loss of appetite, nausea, vomiting, fatigue, row thick brown urine, then seek medical advice. Physical examination: fever, scleral yellow dye, rash, liver in the right rib 1.5cm, there is a clear knock pressure tenderness. Dark red tongue, yellow greasy fur, pulse string. Laboratory tests: alanine aminotransferase 210 units, serum alkaline phosphatase 42 gold units / 100ml, serum jaundice index 38 units, HBsAg-negative, patients and their families without a history of hepatitis. Then diagnosed as drug-induced liver damage. Chinese medicine is a liver qi