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目的探讨女性急性心肌梗死(AMI)合并糖尿病患者介入治疗(PCI)手术效果。方法将2003年10月至2006年9月收治的158例女性AMI患者分为糖尿病组(DM组,67例)和非糖尿病组(ND组,91例),于发病12h内行急诊PCI,比较两组患者的临床和冠状动脉造影特征、PCI成功率及术后并发症发生率。结果①糖尿病组患者血脂异常、未绝经患者、前壁AMI百分比均显著高于ND组(分别为41.8%和25.3%、28.4%和11.0%、68.7%和49.5%,P<0.05)。②糖尿病组患者的梗死相关血管为前降支者显著高于ND组(59.7%和41.6%,P<0.05),糖尿病组3支病变率显著高于ND组(79.1%和45.1%,P<0.01)。③PCI即刻成功率、术中无复流发生率、住院期间PCI术后并发症发生率和病死率两组比较差异均无统计学意义。结论急诊PCI治疗女性AMI合并糖尿病患者可获得良好的近期疗效。
Objective To investigate the effect of interventional therapy (PCI) on female acute myocardial infarction (AMI) with diabetes mellitus. Methods One hundred and eighty female AMI patients who were admitted to our hospital from October 2003 to September 2006 were divided into diabetic group (DM group, 67 cases) and non-diabetic group (ND group, 91 cases). Emergency PCI was performed within 12 hours of onset, Group clinical and coronary angiographic features, PCI success rate and postoperative complication rate. Results ① In patients with diabetes mellitus, the percentage of AMI in the anterior wall was significantly higher than that in the ND group (41.8% and 25.3%, 28.4% and 11.0%, 68.7% and 49.5%, respectively; P <0.05). ② The infarct-related blood vessels in the diabetic group were significantly higher than those in the ND group (59.7% and 41.6%, P <0.05), respectively. The three lesions in the diabetic group were significantly higher than those in the ND group (79.1% and 45.1%, P < 0.01). ③PCI immediate success rate, intraoperative no-reflow incidence, postoperative PCI complications and mortality in the two groups were no significant difference between the two groups. Conclusions Emergency PCI can achieve good short-term curative effect in women with AMI and diabetes mellitus.