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在过去十年,为了评定洋地黄的最佳治疗剂量及精确诊断洋地黄中毒,医学家介绍过多种测定血清之心脏醣甙的方法。血清之心脏醣甙水平的临床意义是以血液和组织之间洋地黄含量有合理的相互关系这一事实作为根据的,因此该血液洋地黄含量水平反映全身及心肌洋地黄浓度。Doherty等人在这方面获得了重要资料,他们在动物及人类观察到血液和心肌地高辛水平之间相对恒定的比率。目前,一般同意见确诊为洋地黄中毒的病例较无中毒者都明显地有较高的血清或血浆之心脏醣甙。但两者之间的血清或血浆心脏醣甙水平的重迭仍不可避免。在难以处理的充血性心力衰竭和或多种复杂
In the past decade, physicians have introduced various methods of determining serum glycosides in order to assess the best therapeutic dose of digitalis and to diagnose digitalis accurately. The clinical significance of serum cardiac glycoside levels is based on the fact that there is a reasonable correlation of digitalis between blood and tissue, and therefore this digitalis blood level reflects both systemic and myocardial digitalis concentrations. Doherty et al. Obtained important information in this regard that they observed a relatively constant ratio between blood and myocardial digoxin levels in animals and humans. Currently, it is generally agreed that patients diagnosed with digitalis poisoning have significantly higher serum or plasma cardioglycosides than those without toxicity. However, the overlap of serum or plasma glycoside levels between the two is still unavoidable. In difficult-to-treat congestive heart failure and or multiple complications