溶血性尿毒症性综合征(HUS)是一罕见而严重疾病,其特征是微血管病性溶血性贫血、血小板减少和急性肾功能衰竭。本病主要发生在儿童,但亦偶见于成人。成人通常发生于产后或妇女应用口服避孕药,因为这可使血小板损伤和激活凝血系统,提示成人 HUS 病因中,异常止血起重要作用。本文观察11例成人10余年长病程 HUS 的临床经过,报告如下。11例中,女9,男2例,发病年龄23～40岁。8例妇女发生于产后(其中4例妊娠合并先兆子痫,2例胎盘早剥,2例正常妊娠行剖腹产),1例口服避孕药;2例男性发病原因未明,其中1例开始时有呕吐及腹泻。无1例有 HUS 家族史。初诊时全部有高 Hemolytic uremic syndrome (HUS) is a rare and severe disease characterized by microangiopathic hemolytic anemia, thrombocytopenia and acute renal failure. The disease occurs mainly in children, but occasionally in adults. Adults typically occur after birth or in women using oral contraceptives as this can damage platelets and activate the coagulation system, suggesting that hemostasis may play an important role in the pathogenesis of adult HUS. This article observed 11 cases of adult over 10 years of clinical course of HUS, the report is as follows. In 11 cases, 9 were males and 2 were males. The age of onset was 23-40 years old. 8 cases occurred in postpartum women (4 cases of pregnancy with preeclampsia, 2 cases of placental abruption, 2 cases of normal pregnancy caesarean section), 1 case of oral contraceptives; 2 cases of male etiology is unknown, of which 1 case started with vomiting And diarrhea. None had HUS family history. All newly diagnosed high