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目的观察中药心复康和卡托普利对心梗再灌注心肌细胞损伤后血液流变性及左室舒张功能的影响。方法25例急性心肌梗塞(AMI)再灌注心肌损伤患者,每次给服心复康200毫升 1日 2次和 Captopril12.5mg每日1次。检测其治疗前后血液流变学、ECG及超声心动图等各项指标,结果进行自身对照。结果使用心复康和卡托普利治疗后,全血粘度(低切,19.85±5.20降至18.58±5.10)、还原粘度由9.25±2.21明显降至7.10±2.17,全血粘度(高切由5.45±0.54降至5.24±0.44)、血浆粘度由 1.98±0.18降至 1.55±0.15)、HCT(由0.55±0.04降至0.42±0.02)。RAI由3.28±0.75降至2.55±0. 52,而 IR由 8. 53±0. 52明显降至 6. 20±0. 45, Fib由3.15±0.±44降至 2.68±0.35和 ESR、ESRK等指标均有降低。E从比值治疗后高于治疗前(1.24±0.40-0.94±0.52),治疗后PE(cm/s)高于治疗前(72.4±12.6-60.5±12.4),PA(cm/s)治疗后亦高于治疗前(70.2±18.4-63.5±1?
Objective To observe the effect of xifukang and captopril on the hemorheology and left ventricular diastolic function after myocardial cell injury in reperfusion of myocardial infarction. Methods Twenty - five patients with acute myocardial infarction (AMI) were reperfused with myocardial injury. Each time they were given congestive heart failure 200 ml twice a day and captopril 12.5 mg once daily. Before and after treatment, hemorrheology, ECG and echocardiography were detected, and the results were compared with each other. Results After treatment with xifukang and captopril, whole blood viscosity (low cut, 19.85 ± 5.20 down to 18.58 ± 5.10) and reduced viscosity decreased significantly from 9.25 ± 2.21 To 7.10 ± 2.17, the whole blood viscosity (high cut from 5.45 ± 0.54 to 5.24 ± 0.44), plasma viscosity decreased from 1.98 ± 0.18 to 1.55 ± 0.15), HCT (from 0.55 ± 0.04 to 0.42 ± 0.02). RAI decreased from 3.28 ± 0.75 to 2.55 ± 0. 52, and IR by 8. 53 ± 0. 52 significantly reduced to 6. 20 ± 0. 45, Fib from 3.15 ± 0. ± 44 to 2.68 ± 0.35 and ESR, ESRK and other indicators were reduced. E was higher than that before treatment (1.24 ± 0.40-0.94 ± 0.52) after treatment, and PE (cm / s) after treatment was higher than that before treatment (72.4 ± 12.6-60. 5 ± 12.4), PA (cm / s) after treatment is also higher than before treatment (70.2 ± 18.4-63.5 ± 1?