手足口病是全球性传染病,世界上大多数国家和地区曾有关于此病流行的报道。手足口病流行无明显的地区性。一年四季均可发病,但以夏秋季多见,冬季的发病较为少见。本病常于爆发流行后散在发生,托幼机构是本病流行的主要场所。手足口病常出现间隔2～3年的周期性流行。 Hand, foot and mouth disease is a global epidemic that has been reported in most countries and regions in the world. Hand, foot and mouth disease epidemic no obvious regional. Disease can occur throughout the year, but more common in summer and autumn, the incidence of winter is relatively rare. The disease often occurs after the outbreak of the epidemic, child care institutions is the main place for the epidemic. Hand, foot and mouth disease often occur periodically 2 to 3 years of epidemic.