论文部分内容阅读
目的采用化学计量学分析方法,建立黄芪Astragalus membranaceus药材质量评价体系。方法收集20批不同产地不同品种黄芪药材,建立皂苷、黄酮类成分特征图谱。运用主成分分析、聚类分析方法深入研究不同黄芪药材中化学成分量的变化趋势及规律。结果 17个特征成分中,黄芪皂苷Ⅰ、黄芪皂苷ⅣV、芒柄花素和2个未知皂苷成分的差异显著,可作为区分不同产地或不同品种黄芪的关键性指标成分。结论通过化学计量学分析方法,建立的黄芪药材中皂苷、黄酮类成分评价体系专属性强、准确性高,可有效控制和评价黄芪药材质量。
Objective To establish the quality evaluation system of astragalus membranaceus by stoichiometry. Methods Twenty batches of Astragalus membranaceus from different areas were collected to establish the characteristic map of saponin and flavonoids. Principal component analysis and cluster analysis were used to study the changing trend and regularity of chemical components in different Astragalus membranaceus. Results Among the 17 characteristic components, astragaloside Ⅰ, astragaloside IVV, formononetin and two unknown saponin components were significantly different, which could be used as key index components to distinguish Astragalus from different origins or varieties. Conclusion Through the method of stoichiometry, the evaluation system of saponin and flavonoids in Astragalus membranaceus was established with high specificity and high accuracy, which can effectively control and evaluate the quality of Radix Astragali.