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目的探讨肺炎支原体咽拭子快速培养法与血清肺炎支原体被动凝集法在临床中不同时间的应用价值。方法将76例临床确诊肺炎支原体感染的患者随机分为快速培养组和被动凝集组各38例。分别于2组患者病程5d内及病程7d后取快速培养组患者的咽拭子做快速培养,取被动凝集组患者的血清做被动凝集,观察并比较不同检测时间内2组患者阳性率。结果病程5d内快速培养组患者阳性率44.74%高于被动凝集组的21.05%,差异有统计学意义(P<0.05);病程7d或被动凝集组阳性率97.37%高于快速培养组63.16%,差异有统计学意义(P<0.05)。结论不同检测时间,快速培养法与被动凝集法对肺炎支原体的敏感性不同,临床医师应根据时间选择合适的方法进行检测。
Objective To investigate the clinical value of rapid culture of throat swabs Mycoplasma pneumoniae and passive agglutination of Mycoplasma pneumoniae in clinical practice. Methods 76 patients with clinically diagnosed Mycoplasma pneumoniae infection were randomly divided into rapid culture group and passive agglutination group of 38 cases. The throat swabs of patients in rapid culture group were rapidly cultured within 5 days after the course of disease and 7 days after the course of disease, respectively. The serum of patients in passive agglutination group was agglutinated by passive agglutination. The positive rate of the two groups was observed and compared. Results The positive rate of rapid culture group within 5 days was 44.74% higher than that of passive agglutination group (21.05%), the difference was statistically significant (P <0.05). The positive rate of 97.37% in 7d or passive agglutination group was higher than that of rapid culture group (63.16% The difference was statistically significant (P <0.05). Conclusion Different detection time, rapid culture method and passive agglutination method have different sensitivities to Mycoplasma pneumoniae. Clinicians should select suitable methods according to the time.