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目的观察健脾解毒汤结合化疗对胃癌术后患者的影响。方法将69例胃癌术后患者按照队列研究分为两组;对照组32例采用单纯化疗治疗,观察组37例采用化疗药物结合健脾解毒汤治疗。观察两组中医证候疗效、生存质量、复发和毒副反应情况。结果中医证候疗效、生存质量、毒副反应的改善,观察组优于对照组(P<0.05);两组复发率比较无显著性差异(P>0.05)。结论健脾解毒汤联合化疗可提高胃癌术后患者中医证候疗效和生存质量,减轻化疗毒副反应。
Objective To observe the effect of Jianpi Jiedu Decoction combined with chemotherapy on postoperative patients with gastric cancer. Methods 69 cases of postoperative patients with gastric cancer were divided into two groups according to the cohort study. In the control group, 32 cases were treated with chemotherapy alone and 37 cases in the observation group were treated with chemotherapy combined with Jianpi Jiedu Decoction. The curative effect, quality of life, recurrence and toxicity were observed in two groups of TCM syndromes. Results The efficacy of traditional Chinese medicine, quality of life, and side effects were improved in observation group than in control group (P <0.05). There was no significant difference in relapse rate between two groups (P> 0.05). Conclusions Jianpi Jiedu Decoction combined with chemotherapy can improve the curative effect and quality of life of patients with traditional Chinese medicine after gastric cancer operation and reduce the toxic and side effects of chemotherapy.