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目的分析原发性阴道恶性肿瘤患者预后相关因素。方法选取2009年我院收治的原发性阴道恶性肿瘤患者23例,给予放射治疗、手术治疗、化学治疗相结合的综合性治疗方法。患者随访3年,记录其生存情况。结果不同肿瘤类型、肿瘤直径、国际妇产科联盟(FIGO)分期、病理分级、阴道受侵长度患者生存率比较,差异均有统计学意义(P<0.05);其中鳞癌、肿瘤直径<2 cm、FIGO分期Ⅰ期、病理分级Ⅰ级及阴道受侵长度<1/3的患者生存率高于同组的其他分型(P<0.05)。结论原发性阴道恶性肿瘤患者生存情况与其肿瘤类型、肿瘤直径、FIGO分期、病理分级、阴道受侵长度等因素相关,尽早确诊并给予有效治疗,对提高患者预后、延长生存时间、保障生活质量与生命安全有重要意义。
Objective To analyze the prognostic factors of patients with primary vaginal cancer. Methods Twenty-three patients with primary vaginal cancer admitted to our hospital in 2009 were selected and given a combination of radiotherapy, surgery and chemotherapy. Patients were followed up for 3 years to record their survival. Results The survival rates of patients with different tumor types, tumor diameter, FIGO staging, pathological grade and vaginal invasion length were significantly different (P <0.05). Among them, squamous cell carcinoma with tumor diameter <2 The survival rates of patients with stage Ⅰ, FIGO stage Ⅰ, stage Ⅰ and vaginal invasion less than 1/3 were higher than those in other groups (P <0.05). Conclusion The survival of patients with primary vaginal malignant tumor is related to the tumor type, tumor diameter, FIGO stage, pathological grade, vaginal invasion length and other factors, and early diagnosis and effective treatment, to improve patient prognosis, prolong survival and ensure quality of life And life safety is of great significance.