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患者男,32岁,因诊断为精神分裂症于1984年5月10日首次住院。自入院日起,连续二日接受奋乃静口服12毫克/日和肌肉注射10毫克/日治疗,第三日晨七时许。突然坐立不安,兴奋躁动,继之流涎、伸舌、颈项扭转痉挛、四肢震颤。当晚八时出现神志不清、呼吸急促、颜面潮红、出汗、小便失禁、类癫痫样大发作5～6次。检查体温39.°6C,呼吸28次/分,脉博102次/分,血压140/110(入院时为110/70),意识呈浅昏迷状态,发育营养良好,心肺无特殊,肝脾不肿大,瞳孔缩小,对光反应迟钝,颈部有抗力,四肢肌张力增高,腱反射对称性亢进,未引出病理反射。实验室检查:血、尿常规正常。治疗经过:立即停用奋乃静,每日静脉滴
Patient Male, 32 years old, first hospitalized on May 10, 1984 due to diagnosis of schizophrenia. From admission day, on the 2nd consecutive days of perphenazine oral administration of 12 mg / day and intramuscular injection of 10 mg / day treatment, the next morning at about 7 am. Suddenly restless, excited restlessness, followed by salivation, stretch tongue, neck spasm, limb tremor. Appeared unclear at 8:00 that night, shortness of breath, flushing, sweating, urinary incontinence, epilepsy-like episode 5 to 6 times. Check the body temperature 39. ° 6C, breathing 28 beats / min, pulse 102 times / min, blood pressure 140/110 (110/70 admission), consciousness was shallow coma state, well-developed nutrition, no special cardiopulmonary, liver and spleen Enlargement, miosis, slow reaction to light, neck resistance, muscle tension increased limbs, tendon reflex symmetry hyperthyroidism, did not lead to pathological reflex. Laboratory tests: blood, urine, normal. After treatment: stop using perphenazine, daily intravenous drip