溃疡病是消化道常见的一种慢性疾病,常反复发作,而一些药物又可诱发和加重溃疡,所以,有些药对溃疡病人来说应慎用或禁用。第一类是解热镇痛药,如阿司匹林,长期或较大剂量服用可诱发胃溃疡,甚至引起胃出血,这是因为它能抑制前列腺素的合成。前列腺素能使胃酸分泌减少,减少胃酸的刺激和腐蚀作用,当前列腺素合成受到抑制时,胃酸分泌增多,就会加重对胃粘 Canker disease is a common chronic disease of the digestive tract, often repeated attacks, while some drugs can induce and aggravate ulcers, so some drugs should be used with caution or disabled for patients with ulcers. The first category is antipyretic analgesics, such as aspirin, long-term or larger doses can induce gastric ulcer, and even cause stomach bleeding, because it can inhibit prostaglandin synthesis. Prostaglandins can reduce gastric acid secretion, reduce gastric acid stimulation and corrosion, when prostaglandin synthesis is inhibited, increased gastric acid secretion, it will increase the adhesion to the stomach