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目的了解甘肃省2012年甲型肝炎(甲肝)灭活疫苗(Hepatitis A Vaccine,Inactivated;HepA-I)群体性预防接种中,疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的发生特征,评价HepA-I的安全性。方法采用描述性流行病学方法,对AEFI监测系统中的相关数据进行统计分析。结果甘肃省2012年接种HepA-I 760 451剂,发生AEFI 95例,AEFI报告发生率124.92/100万剂。其中一般反应90例,报告发生率118.35/100万剂,异常反应3例,报告发生率3.94/100万剂,心因性反应2例,报告发生率2.63/100万剂。结论群体性接种HepA-I的AEFI发生率低,HepA-I具有良好的安全性。
Objective To understand the characteristics of suspected AivelIective Events Following Immunization (AEFI) in population vaccination in Hepatitis A (Hepatitis A Vaccine, Inactivated HepA-I) in Gansu Province in 2012, HepA-I safety. Methods Using descriptive epidemiological methods, the data of AEFI monitoring system were statistically analyzed. Results In HepA-I 760 451, 95 cases of AEFI occurred in Gansu Province in 2012, and the incidence of AEFI was 124.92 / 1 million doses. The general reaction of 90 cases, the report of a rate of 118.35 / 1 million doses, 3 cases of abnormal reaction, the report of a rate of 3.94 / 1 million agents, 2 cases of cardiac response, the report incidence of 2.63 / 1 million doses. Conclusion HepA-I group vaccination has a low incidence of AEFI and HepA-I has good safety.