论文部分内容阅读
目的:探讨男性不育症患者血清TNF-α、T、FSH、PRL水平的变化及临床意义。方法:应用放射免疫分析对36例男性不育症患者进行了血清TNF-α、T、FSH、PRL检测,并与35例男性正常人作比较。结果:男性不育症患者血清T水平非常显著地低于男性正常人组(P<0.01),而TNFα-、FSH、PRL水平又非常显著地高于男性正常人组(P<0.01),血清TNF-α水平与T水平呈负相关(r=-0.5184,P<0.01),与FSH、PRL水平呈正相关(r=0.6184、0.5925,P<0.01)。结论:检测男性不育症患者血清TNF-α、T、FSH、PRL水平的变化对诊断、预后判断及治疗均有较大的临床价值。
Objective: To investigate the changes and clinical significance of serum TNF-α, T, FSH and PRL levels in male infertility patients. Methods: Serum TNF-α, T, FSH and PRL levels were measured in 36 male infertility patients by radioimmunoassay and compared with 35 normal male subjects. Results: The level of serum T in male infertility patients was significantly lower than that in male normal subjects (P <0.01), while the levels of TNFα-, FSH and PRL were significantly higher than those in male normal subjects (P <0.01) The level of TNF-α was negatively correlated with T level (r = -0.5184, P <0.01), and positively correlated with the level of FSH and PRL (r = 0.6184,0.5925, P <0.01). Conclusion: The changes of serum TNF-α, T, FSH and PRL levels in male infertility patients have great clinical value in diagnosis, prognosis and treatment.